Hotels in Los Santos

Search and compare Los Santos hotels from hundreds of travel sites on HotelsCombined and save.

...and more

Learn why travellers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customie your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Travel insights for hotels in Los Santos

Use these up-to-date, data-driven insights about booking a hotel in Los Santos including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in Los Santos?

The cheapest month to book a hotel in Los Santos is January ($73). Conversely, the most expensive month to stay in Los Santos is April ($335).

What is the cheapest day to stay in a hotel in Los Santos?

The cheapest day to stay in Los Santos is Wednesday ($103). On the other hand, travelers can expect to pay the most on Friday, when the average nightly price is $223.

Cheapest hotels in Los Santos, Panama

Discover affordable stays in Los Santos that provide a quality experience without breaking the bank. Hotels in Los Santos can be found for as low as $88 per night. There is currently one property in Los Santos that can be booked for this price. Casa Loma is one of the hotels that can be booked for the lowest price in Los Santos. Price data was last updated on 3 April 2026
For those on a budget, these are the cheapest hotels available in Los Santos for the selected dates. If you have flexibility with arrival and departure, use the search form to compare prices for other dates.
Calle Principal, Frente Policia Nacional, Pedasí, Panama
0.0 km from city centre
Free Wi-Fi
Parking
$88
Avg. per night
Camino a Puerto Escondido, Pedasí, Panama
10.2 km from city centre
Free Wi-Fi
Parking
$104
Avg. per night
Belisario Porras Avenue, Las Escobas del Venado, Panama
0.9 km from city centre
Airport shuttle
$118
Avg. per night
Calle Moises Espino, Las Tablas, Panama
0.3 km from city centre
Free Wi-Fi
Parking
$128
Avg. per night
Playa Venao 1, Las Escobas del Venado, Panama
1.3 km from city centre
Free Wi-Fi
Airport shuttle
$138
Avg. per night
Playa Venao, Las Escobas del Venado, Panama
0.8 km from city centre
Free Wi-Fi
Parking
$190
Avg. per night
Las Escobas del Venado, Panama
1.8 km from city centre
Air conditioning
$190
Avg. per night
Playa Venao, Las Escobas del Venado, Panama
0.8 km from city centre
Free Wi-Fi
$319
Avg. per night
Calle Principal, Cambutal, Panama
2.9 km from city centre
$454
Avg. per night

Where to stay in Los Santos

Explore different neighbourhoods and areas within Los Santos to find the perfect location for your stay. Map data was last updated on 3 April 2026.
Scroll through the map to find hotels close to the Los Santos neighbourhood(s) you plan on visiting. Users can click on a hotel's name to find more information about it, such as price, reviews, and amenities, and also find different deals for the property.

Facts about staying in Los Santos

Find useful tips and insights about staying in Los Santos to help you make the most of your experience. FAQs were last updated on 3 April 2026.
  • Where is the best place to stay in Los Santos?

    When visiting Los Santos, consider checking out Pedasí and Cambutal as some of the most sought after locations.

  • What are the best hotels in Los Santos?

    Casa Lajagua, rated with a score of 8.8 from 326 reviewers, is one of the most popular hotels in Los Santos. Other top stays include Selina Playa Venao, with an average rating of 7.9 from 1,878 reviewers, and Selina River Venao, with a score of 7.9 from 883 reviewers.

Find better results for your stay in Los Santos

Consider these popular 4-star hotels in Los Santos

Stay at one of these Los Santos 4-star hotels that users have found on HotelsCombined.