Hotels in South San Francisco

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Popular hotels in South San Francisco

Discover well-known properties in South San Francisco that are favoured by visitors more than others. There are 114 hotels in South San Francisco and price data was last updated on 25 July 2025. The average price for a hotel in South San Francisco is $220/night.
These are some of the hotels in South San Francisco with the highest demand. Users seeking more options can adjust the settings in the search form at the top of the page.
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300 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.195% CA Tourism Assessment Fees and 0.75% San Mateo TMD Assessment Fees The Hampton Inn South San Francisco-Airport hotel in California is ideally located just 1.5 miles north of the airport off Grand Avenue/South San Francisco off Highway 101. The hotel offers courtesy transportation to and from the airport. Transportation to our BART station is also available. The hotel is 9 miles away from the New Golden State Warriors Chase Center and 10 miles away from the Oracle Park, San Francisco's Giants home. Warm to our California hospitality in one of our 100 guest rooms with comfortable queen or king beds. Our spacious and attractive hotel rooms include all the amenities you expect including our large, comfortable workspaces. Our affordable rates are designed to make your stay a wonderful experience from the moment you check in. From communications to accommodations, you will find our amenities the perfect companion for the business or leisure traveler. While at the Hampton Inn San Francisco-Airport hotel, get started each morning with our hot complimentary breakfast buffet that is served from 6:00 am - 10:00 am everyday. Or, if you have early check-out, get one of our On The Run breakfast! Everything you want in a quality hotel for a fraction of what you would expect to pay. Whether a room for yourself, or our value saving packages: Park, Stay and Go, Shop and Drop, City Tour, Wine Tour, Movie On Us or a conference setting for your group, our professional staff is eager to assist you with planning. Our San Francisco, California hotel received the Top 10% Circle of Excellence Award two years in a row and were also a winner in Product and Service. We love having you here at the Hampton Inn San Francisco-Airport hotel in California!
Free Wi-Fi
Airport shuttle
8.2
Excellent
731 reviews
Location
0.6 km from city centre
380 South Airport Boulevard, South San Francisco, CA, United States
Just 1.5 miles from San Francisco International Airport, the Best Western Plus Grosvenor Airport Hotel is the perfect hotel in South San Francisco, CA for business travelers and vacationers alike, with easy access to must-see attractions like nearby Fisherman's Wharf, Pier 39, Union Square, Chinatown, and Golden Gate Park plus complimentary shuttle service to SFO. Our rooms are beautifully appointed in warm reds and clean whites. Beds are covered with triple sheeting and duvets for your comfort. Your room’s flat-screen TV and free high-speed Internet access help you stay plugged in, while the coffee maker, refrigerator, and microwave let you feel a little more at home. From May until October, you can splash down in our heated outdoor pool. Planning an event? Our flexible meeting spaces can accommodate up to 400. Here we start your day with a complimentary full hot breakfast. Fill up with eggs, breakfast meat, French toast, biscuits and gravy, pastries, fruit, yogurt, and 100% Arabica coffee. Later in the day, visit the Brass Elephant Restaurant & Lounge for American comfort food classics, nightly happy hour specials, and all the games on TV screens as big as 12 feet. Ready to eat, but not to go anywhere? We also offer room service. Whether you’re visiting for a 49ers or Giants game, attending an event at the South San Francisco Conference Center, here for business in Silicon Valley, or simply visiting our wealth of cultural attractions, the Best Western Grosvenor Plus Airport Hotel is the right choice for style, comfort, and value. Book your visit to San Francisco and the Best Western Plus Grosvenor Airport Hotel today.
Free Wi-Fi
7.7
Good
3234 reviews
Location
1.3 km from city centre
670 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.195% CA Tourism Assessment and.75% San Francisco Peninsula Tourism Marketing District. The Hilton Garden Inn San Francisco Airport North hotel is located in California's South San Francisco, an area that many Biotech Companies call home. Our neighbors include Genentech, SAP, Amgen, Rigel and Prothena Pharmaceuticals. The Hilton Garden Inn San Francisco Airport North hotel is close to the San Francisco International Airport. While you are here, enjoy the comforts of our spacious guest rooms, including Garden Sleep System bed, complimentary WiFi and hospitality center equipped with microwave, refrigerator and coffeemaker. Treat yourself to a meal at The Garden Grille and Bar, order rooms service, or grab a snack at our 24 hour Pavilion Pantry. At Hilton Garden Inn San Francisco Airport North hotel you are close to top local attractions with easy access to Highway 101, eight miles from downtown San Francisco, one mile from Cow Palace and Oyster Point Marina, ten miles from Moscone Center, Union Square, Fisherman's Wharf, ATT Park and only eight miles from many other San Francisco attractions.
Free Wi-Fi
8.3
Excellent
689 reviews
Location
0.9 km from city centre
250 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: San Mateo County Tourism Assessment & California Tourism Assessment The Embassy Suites by Hilton San Francisco Airport Oyster Point is located in South San Francisco, just three miles north of San Francisco International Airport and 10 miles south of downtown San Francisco. Enjoy spacious accommodations in this all-suite hotel that includes a free made to order breakfast. In addition to a modern exercise facility, we offer a relaxing heated indoor pool. We also offer complimentary drinks and snacks at our Evening Reception*. Relax in our tropical atrium and experience our on-site restaurant Two-Fifty. Free WiFi for Hilton Honors members! *Service of alcohol subject to state and local laws. Must be of legal drinking age. *The guaranteed credit card will be authorized for $50, one day prior to arrival.
Pool
8.0
Excellent
1128 reviews
Location
0.6 km from city centre
550 Gateway Boulevard, South San Francisco, CA, United States
Daily Mandatory Charge includes: 0.75% San Mateo TBID Assessment Fees. Right off US-101 in the birthplace of Biotechnology, Home2 Suites by Hilton San Francisco Airport North provides a comfortable stay during your business trip or vacation. Walk to the Genentech campus, or take our complimentary shuttle to and from San Francisco International Airport (SFO), just two miles away. Our hotel is also close to South San Francisco dining and shopping, as well as BART and Caltrain stations. Rest well in our contemporary, spacious suites, offering a living area, in-suite kitchen and free WiFi. A full-size refrigerator, dishwasher, cooktop and dishes make preparing meals easy. Move the furniture to suit your needs, and feel free to bring your pet along on your trip. Fuel your day with free breakfast favorites such as fresh fruit, oatmeal, eggs, cereal and more, as well as hot coffee and tea available 24-hours. If you need a snack, or forgot your toothbrush, visit out Home2 MKT anytime. Business travelers will appreciate our spacious meeting room for up to 55 people, as well as our business services area with free wireless printing. Keep up with your workout routine and run a load of laundry in our Spin2 Cycle facility.
Free Wi-Fi
8.6
Excellent
564 reviews
Location
0.8 km from city centre
1333 Veterans Boulevard, South San Francisco, CA, United States
This design-driven AC Hotel on the San Francisco Bay is all about modern architecture with wonderful waterfront views. Guestrooms feature sleek furnishings and the most comfortable bed you’ll sleep in besides your own. Free WiFi combines with ample amenities including an indoor pool, fitness center, flexible meeting space, and media salons. Our AC Kitchen serves up a European-inspired breakfast, while lunch and dinner in the AC Lounge are flavored with Spanish flair. Karl the Fog cocktails highlight a bar menu focused on tapas. Located in the Cove at Oyster Point, our Bay Area hotel is minutes from SFO Airport; Caltrain and the San Francisco Bay Ferry are less than a mile. Proximity to a hub of biotech companies makes it ideal for business travelers; this airport hotel is adjacent to the San Francisco Bay Trail – with convenient access to Pier 39, The Embarcadero, and Golden Gate Bridge - it’s for leisure travelers, too.
Pool
Free Wi-Fi
8.6
Excellent
557 reviews
Location
1.5 km from city centre
264 South Airport Boulevard, South San Francisco, CA, United States
Elevate your trip when you stay at Four Points by Sheraton Hotel and Suites San Francisco Airport. Our contemporary San Francisco Airport hotel is just one mile from San Francisco International Airport and nine miles from the historic Bay in San Francisco, CA. Discover nearby top attractions like Coit Tower, Cow Palace Arena & Event Center, Oracle Park, Fisherman's Wharf, and Ghirardelli Square. Business travelers appreciate the location of our pet-friendly hotel in South San Francisco Airport near biotechnology companies and other corporations. After a day of working or sightseeing, get in a quick workout at our on-site fitness center and then retreat to one of our renovated hotel suites with luxury bedding, high-speed Wi-Fi, and a flat-panel TV. Whether you're traveling with family, friends, or colleagues, save on your stay when you book a block of hotel rooms. Find everything you need to travel the way you like at Four Points by Sheraton Hotel and Suites San Francisco Airport.
Free Wi-Fi
7.0
Good
282 reviews
Location
0.8 km from city centre
1350 Veterans Boulevard, South San Francisco, CA, United States
Hotel with free breakfast, near San Francisco Bay This smoke-free hotel features an outdoor pool, a fitness center, and a snack bar/deli. Free buffet breakfast, free WiFi in public areas, and a free airport shuttle are also provided. Other amenities include a hot tub, coffee/tea in a common area, and a business center. Weekly housekeeping is available. Sonesta ES Suites San Francisco Airport Oyster Point Waterfront offers 152 accommodations with coffee/tea makers and hair dryers. Accommodations offer separate sitting areas. Pillowtop beds feature Frette Italian sheets and premium bedding. A pillow menu is available. Flat-screen televisions come with premium cable channels and pay movies. Accommodations at this 3-star hotel have kitchens with refrigerators, stovetops, microwaves, and dishwashers. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations and complimentary toiletries. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Change of towels and change of bedsheets can be requested. Housekeeping is provided weekly. An outdoor pool and a hot tub are on site. Other recreational amenities include a fitness center. The recreational activities listed below are available either on site or nearby; fees may apply.
Free Wi-Fi
7.8
Good
400 reviews
Location
1.8 km from city centre
100 Hickey Boulevard, South San Francisco, CA, United States
Motel in South San Francisco with free parking This smoke-free motel features a business center, concierge services, and a 24-hour front desk. Free WiFi in public areas and free self parking are also provided. Other amenities include a vending machine. Travelers Inn offers 20 air-conditioned accommodations with irons/ironing boards and complimentary toiletries. This South San Francisco motel provides complimentary wired and wireless Internet access. Guests can make use of the in-room refrigerators and microwaves. Housekeeping is offered daily and hair dryers can be requested.
Free Wi-Fi
Air conditioning
7.0
Good
233 reviews
Location
4.1 km from city centre
760 El Camino Real, South San Francisco, CA, United States
Motel in South San Francisco with free parking Along with a 24-hour front desk, this smoke-free motel has free self parking and free WiFi in public areas. Other amenities include a vending machine. Americana Inn offers 17 air-conditioned accommodations with coffee/tea makers and hair dryers. Flat-screen televisions are featured in guestrooms. Refrigerators and microwaves are provided. Bathrooms include shower/tub combinations. This South San Francisco motel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.
Free Wi-Fi
Parking
7.8
Good
333 reviews
Location
2.1 km from city centre

Travel insights for hotels in South San Francisco

Use these up-to-date, data-driven insights about booking a hotel in South San Francisco including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in South San Francisco?

The cheapest month to book a hotel in South San Francisco is May ($264). Conversely, the most expensive month to stay in South San Francisco is April ($481).

What is the cheapest day to stay in a hotel in South San Francisco?

The cheapest day to stay in South San Francisco is Wednesday ($264). On the other hand, travelers can expect to pay the most on Monday, when the average nightly price is $449.

How much is a hotel in South San Francisco tonight?

Users have found prices for hotels in South San Francisco tonight starting as low as $118, rising to an average cost of $273, based on searches in the last 72 hours. Prices start from $315 for a 4-star hotel in South San Francisco for tonight.

How much is a South San Francisco hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in South San Francisco this weekend for as little as $139/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as $139/night. For a 4-star hotel in South San Francisco, the cheapest rate recently found was $210/night for this weekend.

Cheapest hotels in South San Francisco, California

Discover affordable stays in South San Francisco that provide a quality experience without breaking the bank. Hotels in South San Francisco can be found for as low as $107 per night. There is currently one property in South San Francisco that can be booked for this price. Travelodge by Wyndham San Francisco Airport North is one of the hotels that can be booked for the lowest price in South San Francisco. Price data was last updated on 25 July 2025
Out of the hotels in South San Francisco we've come across, these properties are priced the lowest. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
326 South Airport Boulevard, South San Francisco, CA, United States
1.1 km from city centre
Free Wi-Fi
$107
Avg. per night
245 South Airport Boulevard, South San Francisco, CA, United States
0.8 km from city centre
Free Wi-Fi
Parking
Airport shuttle
Air conditioning
$123
Avg. per night
111 Mitchell Avenue, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
$151
Avg. per night
721 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
Airport shuttle
$153
Avg. per night
701 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
Parking
$156
Avg. per night
920 El Camino Real, South San Francisco, CA, United States
2.2 km from city centre
Free Wi-Fi
Parking
$165
Avg. per night
1113 Airport Boulevard, South San Francisco, CA, United States
1.2 km from city centre
Free Wi-Fi
$168
Avg. per night
410 South Airport Boulevard, South San Francisco, CA, United States
1.4 km from city centre
Free Wi-Fi
Airport shuttle
$170
Avg. per night
121 East Grand Avenue, South San Francisco, CA, United States
0.3 km from city centre
Free Wi-Fi
$178
Avg. per night
690 Gateway Boulevard, South San Francisco, CA, United States
1.0 km from city centre
Free Wi-Fi
Airport shuttle
$181
Avg. per night
751 Airport Boulevard, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
Air conditioning
$182
Avg. per night
20 Airport Boulevard, South San Francisco, CA, United States
0.5 km from city centre
Free Wi-Fi
$186
Avg. per night
120 Hickey Boulevard, South San Francisco, CA, United States
4.2 km from city centre
Free Wi-Fi
Parking
$186
Avg. per night
1300 Veterans Boulevard, South San Francisco, CA, United States
1.7 km from city centre
Free Wi-Fi
$193
Avg. per night
800 El Camino Real, South San Francisco, CA, United States
2.1 km from city centre
Free Wi-Fi
Air conditioning
$194
Avg. per night

Hotel prices in South San Francisco

Get a sense of the average price and most popular properties to stay in South San Francisco to help you budget for your trip accordingly. Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” badge are the most popular hotels in South San Francisco at attractive prices. Price data was last updated on 25 July 2025.
We've come across the following hotels in South San Francisco with different price and hotel class options. We've highlighted the most popular properties according to our users as well as the best value within each hotel class.
3 stars
300 Gateway Boulevard, South San Francisco, CA, United States
380 South Airport Boulevard, South San Francisco, CA, United States
670 Gateway Boulevard, South San Francisco, CA, United States
111 Mitchell Avenue, South San Francisco, CA, United States
2 stars and under
721 Airport Boulevard, South San Francisco, CA, United States
701 Airport Boulevard, South San Francisco, CA, United States
326 South Airport Boulevard, South San Francisco, CA, United States

Other accommodations in South San Francisco

Find the perfect hostel, theme hotel, or holiday rental for your stay in South San Francisco.
751 Airport Boulevard, South San Francisco, CA, United States
0.6 km from city centre
Free Wi-Fi
Air conditioning
$182
Avg. per night
920 El Camino Real, South San Francisco, CA, United States
2.2 km from city centre
Free Wi-Fi
Parking
$165
Avg. per night
410 South Airport Boulevard, South San Francisco, CA, United States
1.4 km from city centre
Free Wi-Fi
Airport shuttle
$170
Avg. per night
670 Gateway Boulevard, South San Francisco, CA, United States
0.9 km from city centre
Free Wi-Fi
$203
Avg. per night
1300 Veterans Boulevard, South San Francisco, CA, United States
1.7 km from city centre
Free Wi-Fi
$193
Avg. per night

Where to stay in South San Francisco

Explore different neighbourhoods and areas within South San Francisco to find the perfect location for your stay. Map data was last updated on 25 July 2025.
Navigate to the areas in South San Francisco you plan to visit to find hotels that are close by. You can find more information on a particular hotel within the map by clicking on its name.

About South San Francisco

Often referred to as “South City”, this Bay Area city lies in a valley just to the north of the San Francisco International Airport. It boasts impressive views across the bay, with hills that shield it from the fog San Francisco is renowned for and is noted for the large white letters on Sign Hill which have proudly declared it as “South San Francisco, The Industrial City” since 1923.

Grand Avenue is the heart of South San Francisco, lined with buildings dating back to the city’s earliest days including the neo-colonial Georgian City Hall, designed after Philadelphia's Independence Hall, together with the Carnegie Library and the Metropolitan Hotel, built by the Meat Packers Consortium in 1912. Orange Memorial Park is one of the city’s most beautiful green spaces, with picnic grounds, a sculpture garden, children’s playground and Saturday farmer’s market, while its 28-metre tall Wind Harp sculpture stands as the largest aeolian harp in the world. Undoubtedly South San Francisco’s most popular attraction is Sign Hill, with the heritage-listed landmark visible across the peninsula. It’s been recognised as an outstanding example of 20th century “civic boosterism” and the role that local industries have played in not only the regional economy but also the war effort. Today this iconic sign is surrounded by a city park with numerous hiking trails to explore and offers fantastic panoramas across the Bay Area.

South San Francisco is connected to the city of San Francisco, the SFO international airport and the East Bay along the rapid transit system, with free shuttle services between the downtown area and the main BART station. There are also ferry services between the Oyster Point Marina and both Oakland and Alameda in the East Bay area during weekday commuter hours.

The area that is now South San Francisco was originally part of an early 19th century Mexican land grant, before being conceived as an industrial suburb towards the end of the century by a group of influential meat packing companies. Other industries soon moved into the area, including paint manufacturers, lumber and steel yards, brick and pottery works, firmly establishing the city as an industrial hub dubbed “the smokestack capital of the Peninsula”.

Facts about staying in South San Francisco

Find useful tips and insights about staying in South San Francisco to help you make the most of your experience. FAQs were last updated on 25 July 2025.
  • What are the best hotels in South San Francisco?

    3,234 reviews rated Best Western Plus Grosvenor Airport Hotel with an average score of 7.7/10. It may also be worth looking into the Comfort Inn & Suites San Francisco Airport North, which received a rating of 7.2/10 from 1,616 reviews. Four Points by Sheraton Hotel and Suites San Francisco Airport could also be a good option, with a score of 7.0/10 from 282 reviews.

  • What is a good hotel near Embassy Suites by Hilton San Francisco Airport?

    Reviews of Best Western Plus Grosvenor Airport Hotel recommend it as a good place to stay near Embassy Suites by Hilton San Francisco Airport, scoring 7.7/10 from 3,234 ratings.

  • What is a good hotel in South San Francisco near Sign Hill Park?

    Embassy Suites by Hilton San Francisco Airport Oyster Point is the most recommended hotel near Sign Hill Park on HotelsCombined (scoring 8.0 over 1,128 reviews).

  • Is there a good hotel near South San Francisco Convention Center?

    If you’re planning to stay near South San Francisco Convention Center, you should consider Best Western Plus Grosvenor Airport Hotel, which has a score of 7.7 from 3,234 reviews.

  • Are there any hotels in South San Francisco close to San Francisco?

    The closest hotel to San Francisco is Best Western Plus Grosvenor Airport Hotel, which is located 1.3 km away from the city centre.

  • What are some other cities to stay in when visiting California?

    In addition to South San Francisco, travellers opt to visit Los Angeles when visiting California. Anaheim is also a popular choice to visit.

  • How many hotels are there in South San Francisco?

    In total, there are 114 hotels to choose from in South San Francisco, compared to 118,360 properties in California.

  • What are the most popular landmarks to visit in South San Francisco?

    The most popular landmarks in South San Francisco are Embassy Suites by Hilton San Francisco Airport (in South San Francisco), Sign Hill Park (in South San Francisco), and South San Francisco Convention Center (in South San Francisco) according to our user data. If you plan to visit any of these, we recommend finding a hotel nearby to cut down on travel time.

See more FAQs

Find better results for your stay in South San Francisco

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